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Intracranial MEMS-Based Temozolomide Delivery in a 9L Rat Gliosarcoma Model

Primary malignant brain tumors (BT) are the most common and aggressive malignant brain tumor. Treatment of BTs is a daunting task with median survival just at 21 months. Methods of localized delivery have achieved success in treating BT by circumventing the blood brain barrier and achieving high con...

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Detalles Bibliográficos
Publicado en:Biomaterials
Autores principales: Masi, Byron C., Tyler, Betty M., Bow, Hansen, Wicks, Robert T., Xue, Yuan, Brem, Henry, Langer, Robert, Cima, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404638/
https://ncbi.nlm.nih.gov/pubmed/22591609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.04.048
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