Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain

Metastases represent the most common brain tumors in adults. Surgical resection alone results in 45% recurrence and is usually accompanied by radiation and chemotherapy. Adequate chemotherapy delivery to the CNS is hindered by the blood–brain barrier. Efforts at delivering chemotherapy locally to gl...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Upadhyay, Urvashi M., Tyler, Betty, Patta, Yoda, Wicks, Robert, Spencer, Kevin, Scott, Alexander, Masi, Byron, Hwang, Lee, Grossman, Rachel, Cima, Michael, Brem, Henry, Langer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234553/
https://ncbi.nlm.nih.gov/pubmed/25349381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313420110
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