ET-37 EFFICACY OF INTRACRANIAL DELIVERY OF DICHLOROACETATE AND CARBOPLATIN VIA AN LCP POLYMER MICROCAPSULE DEVICE IN AN EXPERIMENTAL GLIOMA MODEL

BACKGROUND: Multi-targeted therapy is a promising strategy for patients with glioblastoma and controlled delivery of these chemotherapeutics is crucial for effective intracranial chemotherapy. Studies combining platinum pharmacophores with apoptosis inducers, such as Dichloroacetae (DCA), suggest th...

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Détails bibliographiques
Auteurs principaux: Mangraviti, Antonella, Jin, Yike, Sy, Jay, Wang, Yuan, Raghavan, Tula, Hastings-Spaine, Lindsey, Olivi, Alessandro, Tyler, Betty, Brem, Henry
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218134/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.37
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