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Radiosensitization of malignant gliomas following intracranial delivery of paclitaxel biodegradable polymer microspheres: Laboratory investigation

OBJECT: The aim of this study was to demonstrate that paclitaxel could function as a radiosensitizer for malignant glioma in vitro and in vivo. METHODS: The radiosensitizing effect of paclitaxel was tested in vitro using the human U373MG and rat 9L glioma cell lines. Cell cycle arrest in response to...

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Detalhes bibliográficos
Publicado no:J Neurosurg
Main Authors: Gabikian, Patrik, Tyler, Betty M., Zhang, Irma, Li, Khan W., Brem, Henry, Walter, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322932/
https://ncbi.nlm.nih.gov/pubmed/24605841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2014.1.JNS13235
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