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Biodegradable zwitterionic sulfobetaine polymer and its conjugate with paclitaxel for sustained drug delivery

A fully biodegradable zwitterionic polymer and the corresponding conjugate with paclitaxel (PTX) were synthesized as promising biomaterials. Allyl-functionalized polylactide (PLA) was employed as the precursor of polymer backbones. UV-induced thiol-ene reaction was conducted to conjugate thiol-funct...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Sun, Haotian, Chang, Michael Yu Zarng, Cheng, Wei-I, Wang, Qing, Commisso, Alex, Capeling, Meghan, Wu, Yun, Cheng, Chong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682198/
https://ncbi.nlm.nih.gov/pubmed/29030301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.10.016
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