A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging

A multifunctional biodegradable brush polymer-drug conjugate (BPDC) is developed for the co-delivery of hydrophobic paclitaxel (PTX) and hydrophilic gemcitabine (GEM) chemotherapeutics, as well as a tumor imaging agent. A novel ternary copolymer of conventional, acetylenyl-functionalized and allyl-f...

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Vydáno v:Nanoscale Adv
Hlavní autoři: Sun, Haotian, Yan, Lingyue, Chang, Michael Yu Zarng, Carter, Kevin A., Zhang, Runsheng, Slyker, Leigh, Lovell, Jonathan F., Wu, Yun, Cheng, Chong
Médium: Artigo
Jazyk:Inglês
Vydáno: RSC 2019
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451085/
https://ncbi.nlm.nih.gov/pubmed/32864564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9na00282k
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