Leflunomide Sustained Skin Delivery Based on Sulfobetaine-Modified Chitosan Nanoparticles Embedded in Biodegradable Polyesters Films

The aim of the present study was to prepare a leflunomide (LFD) sustained release transdermal delivery system for the treatment of psoriasis. In this context, LFD-loaded nanoparticles (NPs) based on either neat chitosan (CS) or CS modified with [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammon...

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Vydáno v:Polymers (Basel)
Hlavní autoři: Nanaki, Stavroula G., Christodoulou, Evi, Bikiaris, Nikolaos D., Kapourani, Afroditi, Kontogiannopoulos, Konstantinos N., Vergkizi-Nikolakaki, Souzan, Barmpalexis, Panagiotis
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003864/
https://ncbi.nlm.nih.gov/pubmed/33800966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym13060960
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