TRAIL RECEPTOR DELETION IN MICE SUPPRESSES THE INFLAMMATION OF NUTRIENT EXCESS

BACKGROUND & AIMS: Low-grade chronic inflammation is a cardinal feature of the metabolic syndrome, yet its pathogenesis is not well defined. The purpose of this study was to examine the role of TRAIL receptor (TR) signaling in the pathogenesis of obesity-associated inflammation utilizing mice wi...

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Vydáno v:J Hepatol
Hlavní autoři: Idrissova, Leila, Malhi, Harmeet, Werneburg, Nathan W., LeBrasseur, Nathan K., Bronk, Steve F., Fingas, Christian, Tchkonia, Tamar, Pirtskhalava, Tamar, White, Thomas A., Stout, Michael B., Hirsova, Petra, Krishnan, Anuradha, Liedtke, Christian, Trautwein, Christian, Finnberg, Niklas, El-Deiry, Wafik S., Kirkland, James L., Gores, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404200/
https://ncbi.nlm.nih.gov/pubmed/25445398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.11.033
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