Death Receptor 5 Signaling Promotes Hepatocyte Lipoapoptosis

Nonalcoholic steatohepatitis is characterized by hepatic steatosis, elevated levels of circulating free fatty acids (FFA), endoplasmic reticulum (ER) stress, and hepatocyte lipoapoptosis. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor 5 (DR5) is significantly elevated...

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Main Authors: Cazanave, Sophie C., Mott, Justin L., Bronk, Steven F., Werneburg, Nathan W., Fingas, Christian D., Meng, X. Wei, Finnberg, Niklas, El-Deiry, Wafik S., Kaufmann, Scott H., Gores, Gregory J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234758/
https://ncbi.nlm.nih.gov/pubmed/21941003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.280420
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