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Nuclear entry of nonviral vectors

Nonviral gene delivery is limited to a large extent by multiple extracellular and intracellular barriers. One of the major barriers, especially in nondividing cells, is the nuclear envelope. Once in the cytoplasm, plasmids must make their way into the nucleus in order to be expressed. Numerous studi...

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Détails bibliographiques
Publié dans:Gene Ther
Auteurs principaux: Dean, DA, Strong, DD, Zimmer, WE
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403635/
https://ncbi.nlm.nih.gov/pubmed/15908994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302534
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