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Progress and prospects: nuclear import of nonviral vectors

The nuclear envelope represents a key barrier to successful nonviral transfection and gene therapy both in vitro and in vivo. Although the main purpose of the nuclear envelope is to partition the cell to maintain cytoplasmic components in the cytoplasm and nuclear components, most notably genomic DN...

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Detalhes bibliográficos
Main Authors: Lam, AP, Dean, DA
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084667/
https://ncbi.nlm.nih.gov/pubmed/20200566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.31
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