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Nuclear entry of nonviral vectors

Nonviral gene delivery is limited to a large extent by multiple extracellular and intracellular barriers. One of the major barriers, especially in nondividing cells, is the nuclear envelope. Once in the cytoplasm, plasmids must make their way into the nucleus in order to be expressed. Numerous studi...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Dean, DA, Strong, DD, Zimmer, WE
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403635/
https://ncbi.nlm.nih.gov/pubmed/15908994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302534
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