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In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?

The promise of cancer gene therapeutics is hampered by difficulties in the in vivo delivery to the targeted tumor cells, and systemic delivery remains to be the biggest challenge to be overcome. Here, we concentrate on systemic in vivo gene delivery for cancer therapy using nonviral vectors. In this...

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Autori principali: Zhang, Yuan, Satterlee, Andrew, Huang, Leaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392980/
https://ncbi.nlm.nih.gov/pubmed/22525514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.79
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