Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity

A number of drugs and herbal compounds have been documented to cause hepatoxicity. Schisandrin B (Sch B) is an active dibenzocyclooctadiene isolated from Schisandrae fructus, with a wide array of pharmacological activities. However, the potential hepatotoxicity of Sch B is a major safety concern, an...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Yi, Zhou, Zhi-Wei, Jin, Hua, Hu, Chengbin, He, Zhi-Xu, Yu, Zhi-Ling, Ko, Kam-Ming, Yang, Tianxin, Zhang, Xueji, Pan, Si-Yuan, Zhou, Shu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403607/
https://ncbi.nlm.nih.gov/pubmed/25926716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S77071
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