The nsp1, nsp13, and M Proteins Contribute to the Hepatotropism of Murine Coronavirus JHM.WU

Mouse hepatitis virus (MHV) isolates JHM.WU and JHM.SD promote severe central nervous system disease. However, while JHM.WU replicates robustly and induces hepatitis, JHM.SD fails to replicate or induce pathology in the liver. These two JHM variants encode homologous proteins with few polymorphisms,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Zhang, Rong, Li, Yize, Cowley, Timothy J., Steinbrenner, Adam D., Phillips, Judith M., Yount, Boyd L., Baric, Ralph S., Weiss, Susan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403414/
https://ncbi.nlm.nih.gov/pubmed/25589656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03535-14
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