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Replicase Genes of Murine Coronavirus Strains A59 and JHM Are Interchangeable: Differences in Pathogenesis Map to the 3′ One-Third of the Genome

The important roles of the spike protein and other structural proteins in murine coronavirus (MHV) pathogenesis have been demonstrated; however, the role of the replicase gene remains unexplored. We assessed the influence of the replicase genes of the highly neurovirulent MHV-JHM strain and the hepa...

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Detalhes bibliográficos
Main Authors: Navas-Martin, Sonia, Brom, Maarten, Chua, Ming-Ming, Watson, Richard, Qiu, Zhaozhu, Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797483/
https://ncbi.nlm.nih.gov/pubmed/17079303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01944-06
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