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The nsp1, nsp13, and M Proteins Contribute to the Hepatotropism of Murine Coronavirus JHM.WU

Mouse hepatitis virus (MHV) isolates JHM.WU and JHM.SD promote severe central nervous system disease. However, while JHM.WU replicates robustly and induces hepatitis, JHM.SD fails to replicate or induce pathology in the liver. These two JHM variants encode homologous proteins with few polymorphisms,...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Zhang, Rong, Li, Yize, Cowley, Timothy J., Steinbrenner, Adam D., Phillips, Judith M., Yount, Boyd L., Baric, Ralph S., Weiss, Susan R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403414/
https://ncbi.nlm.nih.gov/pubmed/25589656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03535-14
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