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Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion

The coronavirus (CoV) S protein requires cleavage by host cell proteases to mediate virus-cell and cell-cell fusion. Many strains of the murine coronavirus mouse hepatitis virus (MHV) have distinct, S-dependent organ and tissue tropisms despite using a common receptor, suggesting that they employ di...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Phillips, Judith M., Gallagher, Tom, Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375694/
https://ncbi.nlm.nih.gov/pubmed/28148786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-16
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