Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody

The extracellular domain of influenza A virus matrix protein 2 (M2e) is conserved and is being evaluated as a quasiuniversal influenza A vaccine candidate. We describe the crystal structure at 1.6 Å resolution of M2e in complex with the Fab fragment of an M2e-specific monoclonal antibody that protec...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cho, Ki Joon, Schepens, Bert, Seok, Jong Hyeon, Kim, Sella, Roose, Kenny, Lee, Ji-Hye, Gallardo, Rodrigo, Van Hamme, Evelien, Schymkowitz, Joost, Rousseau, Frederic, Fiers, Walter, Saelens, Xavier, Kim, Kyung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403401/
https://ncbi.nlm.nih.gov/pubmed/25609808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02576-14
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