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Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral potential. Two of them inhibited the NA activity and in vitro replication of clad...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135927/ https://ncbi.nlm.nih.gov/pubmed/24829341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03178-13 |
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