Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies

There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and H3N2 viruses of mice that had been immunized...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schotsaert, Michael, Ysenbaert, Tine, Smet, Anouk, Schepens, Bert, Vanderschaeghe, Dieter, Stegalkina, Svetlana, Vogel, Thorsten U., Callewaert, Nico, Fiers, Walter, Saelens, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829898/
https://ncbi.nlm.nih.gov/pubmed/27072615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24402
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