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Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody

We report the crystal structure of the M2 ectodomain (M2e) in complex with a monoclonal antibody that binds the amino terminus of M2. M2e extends into the antibody binding site to form an N-terminal β-turn near the bottom of the paratope. This M2e folding differs significantly from that of M2e in co...

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Vydáno v:J Virol
Hlavní autoři: Cho, Ki Joon, Schepens, Bert, Moonens, Kristof, Deng, Lei, Fiers, Walter, Remaut, Han, Saelens, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702545/
https://ncbi.nlm.nih.gov/pubmed/26468526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02105-15
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