Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Transcriptional reprogramming of proliferative melanoma cells into a phenotypically distinct invasive cell subpopulation is a critical event at the origin of metastatic spreading. Here we generate transcriptome, open chromatin and histone modification maps of melanoma cultures; and integrate this da...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Verfaillie, Annelien, Imrichova, Hana, Atak, Zeynep Kalender, Dewaele, Michael, Rambow, Florian, Hulselmans, Gert, Christiaens, Valerie, Svetlichnyy, Dmitry, Luciani, Flavie, Van den Mooter, Laura, Claerhout, Sofie, Fiers, Mark, Journe, Fabrice, Ghanem, Ghanem-Elias, Herrmann, Carl, Halder, Georg, Marine, Jean-Christophe, Aerts, Stein
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403341/
https://ncbi.nlm.nih.gov/pubmed/25865119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7683
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