Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

The bone microenvironment is composed of niches that house cells across variable oxygen tensions. However, the contribution of oxygen gradients in regulating bone and blood homeostasis remains unknown. Here, we generated mice with either single or combined genetic inactivation of the critical oxygen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Wu, Colleen, Rankin, Erinn B., Castellini, Laura, Fernandez-Alcudia, Javier, LaGory, Edward L., Andersen, Rebecca, Rhodes, Steven D., Wilson, Tremika L.S., Mohammad, Khalid S., Castillo, Alesha B., Guise, Theresa A., Schipani, Ernestina, Giaccia, Amato J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403258/
https://ncbi.nlm.nih.gov/pubmed/25846796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.255000.114
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