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The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis Through the Production of EPO
Osteoblasts are an important component of the hematopoietic microenvironment in bone. However, the mechanisms by which osteoblasts control hematopoiesis remain unknown. We show that augmented HIF signaling in osteoprogenitors results in HSC niche expansion associated with selective expansion of the...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408231/ https://ncbi.nlm.nih.gov/pubmed/22464323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.051 |
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