A comprehensive method for detecting ubiquitinated substrates using TR-TUBE

The identification of substrates for ubiquitin ligases has remained challenging, because most substrates are either immediately degraded by the proteasome or processed by deubiquitinating enzymes (DUBs) to remove polyubiquitin. Although a methodology that enables detection of ubiquitinated proteins...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Yoshida, Yukiko, Saeki, Yasushi, Murakami, Arisa, Kawawaki, Junko, Tsuchiya, Hikaru, Yoshihara, Hidehito, Shindo, Mayumi, Tanaka, Keiji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403176/
https://ncbi.nlm.nih.gov/pubmed/25827227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422313112
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