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Molecular mapping of the heparin-binding exosite of thrombin.

Thrombin contains electropositive patches at opposite poles of the molecule which represent potential exosites for the binding of macromolecular ligands. The function of anion-binding exosite I, the fibrin(ogen) recognition site, has been well described. Anion-binding exosite II, located near the ca...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sheehan, J P, Sadler, J E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1994
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5518
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