A thrombin receptor function for platelet glycoprotein Ib–IX unmasked by cleavage of glycoprotein V
Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous analysis of platelets from GP V-null mice suggested a role for GP V as a negative modulator of platelet activation by thrombin. We now report the mechanism by which thrombi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11172035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1823 |
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