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Molecular mapping of the heparin-binding exosite of thrombin.

Thrombin contains electropositive patches at opposite poles of the molecule which represent potential exosites for the binding of macromolecular ligands. The function of anion-binding exosite I, the fibrin(ogen) recognition site, has been well described. Anion-binding exosite II, located near the ca...

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Detalles Bibliográficos
Autores principales: Sheehan, J P, Sadler, J E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC44027/
https://ncbi.nlm.nih.gov/pubmed/8202520
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