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Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3

Secreted ligands of the insulin family promote cell growth and maintain sugar homeostasis. Insulin release is tightly regulated in response to dietary conditions, but how insulin producing cells (IPCs) coordinate their responses to distinct nutrient signals is unclear. Here, we show that regulation...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Jung, Neufeld, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402654/
https://ncbi.nlm.nih.gov/pubmed/25882208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7846
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