Overexpression of dilp2 causes nutrient-dependent semi-lethality in Drosophila

Insulin/insulin-like growth factor (IGF) plays an important role as a systemic regulator of metabolism in multicellular organisms. Hyperinsulinemia, a high level of blood insulin, is often associated with impaired physiological conditions such as hypoglycemia, insulin resistance, and diabetes. Howev...

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Autors principals: Sato-Miyata, Yukiko, Muramatsu, Keigo, Funakoshi, Masabumi, Tsuda, Manabu, Aigaki, Toshiro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997005/
https://ncbi.nlm.nih.gov/pubmed/24795642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00147
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