Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy

BACKGROUND: Matrix metalloproteinase (MMP) 14 may mediate tumor progression through vascular and immune-modulatory effects. METHODS: Orthotopic murine breast tumors (4T1 and E0771 with high and low MMP14 expression, respectively; n = 5–10 per group) were treated with an anti-MMP14 inhibitory antibod...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Natl Cancer Inst
Autori principali: Ager, Eleanor I., Kozin, Sergey V., Kirkpatrick, Nathaniel D., Seano, Giorgio, Kodack, David P., Askoxylakis, Vasileios, Huang, Yuhui, Goel, Shom, Snuderl, Matija, Muzikansky, Alona, Finkelstein, Dianne M., Dransfield, Daniel T., Devy, Laetitia, Boucher, Yves, Fukumura, Dai, Jain, Rakesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402365/
https://ncbi.nlm.nih.gov/pubmed/25710962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv017
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi