Effects of Vascular-Endothelial Protein Tyrosine Phosphatase Inhibition on Breast Cancer Vasculature and Metastatic Progression

BACKGROUND: The solid tumor microvasculature is characterized by structural and functional abnormality and mediates several deleterious aspects of tumor behavior. Here we determine the role of vascular endothelial protein tyrosine phosphatase (VE-PTP), which deactivates endothelial cell (EC) Tie-2 r...

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Main Authors: Goel, Shom, Gupta, Nisha, Walcott, Brian P., Snuderl, Matija, Kesler, Cristina T., Kirkpatrick, Nathaniel D., Heishi, Takahiro, Huang, Yuhui, Martin, John D., Ager, Eleanor, Samuel, Rekha, Wang, Shuhan, Yazbek, John, Vakoc, Benjamin J., Peterson, Randall T., Padera, Timothy P., Duda, Dan G., Fukumura, Dai, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748004/
https://ncbi.nlm.nih.gov/pubmed/23899555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt164
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