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Vascular normalization as an emerging strategy to enhance cancer immunotherapy

The recent approval of Provenge has brought new hope for anti-cancer vaccine therapies. However, the immunosuppressive tumor microenvironment seems to impair the efficacy of vaccine therapies. The abnormal tumor vasculature creates a hypoxic microenvironment that polarizes inflammatory cells toward...

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Bibliografische gegevens
Hoofdauteurs: Huang, Yuhui, Goel, Shom, Duda, Dan G., Fukumura, Dai, Jain, Rakesh K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655127/
https://ncbi.nlm.nih.gov/pubmed/23440426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4354
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