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Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy

BACKGROUND: Matrix metalloproteinase (MMP) 14 may mediate tumor progression through vascular and immune-modulatory effects. METHODS: Orthotopic murine breast tumors (4T1 and E0771 with high and low MMP14 expression, respectively; n = 5–10 per group) were treated with an anti-MMP14 inhibitory antibod...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Natl Cancer Inst
Main Authors: Ager, Eleanor I., Kozin, Sergey V., Kirkpatrick, Nathaniel D., Seano, Giorgio, Kodack, David P., Askoxylakis, Vasileios, Huang, Yuhui, Goel, Shom, Snuderl, Matija, Muzikansky, Alona, Finkelstein, Dianne M., Dransfield, Daniel T., Devy, Laetitia, Boucher, Yves, Fukumura, Dai, Jain, Rakesh K.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402365/
https://ncbi.nlm.nih.gov/pubmed/25710962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv017
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