B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance

Signaling lymphocyte activation molecules (SLAMs) play an integral role in immune regulation. Polymorphisms in the SLAM family receptors are implicated in human and mouse model of lupus disease. The lupus-associated, somatically mutated and class-switched pathogenic autoantibodies are generated in s...

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Veröffentlicht in:J Immunol
Hauptverfasser: Wong, Eric B., Soni, Chetna, Chan, Alice Y., Domeier, Phillip P., Shwetank, Abraham, Thomas, Limaye, Nisha, Khan, Tahsin N., Elias, Melinda J., Chodisetti, Sathi Babu, Wakeland, Edward K., Rahman, Ziaur S.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402266/
https://ncbi.nlm.nih.gov/pubmed/25801429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403023
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