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TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner

IL-10 producing B cells (B10 cells) play an important immunoregulatory role in various autoimmune and infection conditions. However, the factors that regulate their development and maintenance are incompletely understood. Recently, we and others have established a requirement for TLR7 in promoting a...

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Main Authors: Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Nicholas M. Choi, Chetna Soni, Ziaur S. M. Rahman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-07-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.01632/full
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