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CD40 Signaling Synergizes with TLR-2 in the BCR Independent Activation of Resting B Cells

Conventionally, signaling through BCR initiates sequence of events necessary for activation and differentiation of B cells. We report an alternative approach, independent of BCR, for stimulating resting B (RB) cells, by involving TLR-2 and CD40 - molecules crucial for innate and adaptive immunity. C...

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Detalhes bibliográficos
Main Authors: Jain, Shweta, Chodisetti, Sathi Babu, Agrewala, Javed N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107243/
https://ncbi.nlm.nih.gov/pubmed/21674065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020651
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