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IFNα/βR Signaling Promotes Regulatory T Cell Development and Function Under Stress Conditions

Type I IFNs are a family of cytokines with antiviral and immunomodulatory properties. While the antiviral effects of IFNs are well characterized, their immunomodulatory properties are less clear. To specifically address the effects of type I IFNs on Treg, we studied mixed bone morrow (BM) chimeras b...

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Pubblicato in:J Immunol
Autori principali: Metidji, Amina, Rieder, Sadiye Amcaoglu, Glass, Deborah Dacek, Cremer, Isabelle, Punkosdy, George A., Shevach, Ethan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402260/
https://ncbi.nlm.nih.gov/pubmed/25795758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500036
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