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Potassium Channel Kv1.3 Is Highly Expressed by Microglia in Human Alzheimer’s Disease
Recent genetic studies suggest a central role for innate immunity in Alzheimer’s disease (AD) pathogenesis, wherein microglia orchestrate neuroinflammation. Kv1.3, a voltage-gated potassium channel of therapeutic relevance in autoimmunity, is upregulated by activated microglia and mediates amyloid-m...
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| Pubblicato in: | J Alzheimers Dis |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402159/ https://ncbi.nlm.nih.gov/pubmed/25362031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141704 |
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