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K(v)1.3 inhibition as a potential microglia-targeted therapy for Alzheimer’s disease: preclinical proof of concept
Microglia significantly contribute to the pathophysiology of Alzheimer’s disease but an effective microglia-targeted therapeutic approach is not yet available clinically. The potassium channels K(v)1.3 and K(ir)2.1 play important roles in regulating immune cell functions and have been implicated by...
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| Udgivet i: | Brain |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837198/ https://ncbi.nlm.nih.gov/pubmed/29272333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx346 |
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