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Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease
OBJECTIVE: Microglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca(2+)‐activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing neuroinflammation. METHODS: To determin...
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| Publicado no: | Ann Clin Transl Neurol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6469250/ https://ncbi.nlm.nih.gov/pubmed/31019997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.754 |
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