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Potassium Channel Kv1.3 Is Highly Expressed by Microglia in Human Alzheimer’s Disease

Recent genetic studies suggest a central role for innate immunity in Alzheimer’s disease (AD) pathogenesis, wherein microglia orchestrate neuroinflammation. Kv1.3, a voltage-gated potassium channel of therapeutic relevance in autoimmunity, is upregulated by activated microglia and mediates amyloid-m...

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Podrobná bibliografie
Vydáno v:J Alzheimers Dis
Hlavní autoři: Rangaraju, Srikant, Gearing, Marla, Jin, Lee-Way, Levey, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402159/
https://ncbi.nlm.nih.gov/pubmed/25362031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141704
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