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The p53(R172H) Mutant Does Not Enhance Hepatocellular Carcinoma Development and Progression
Hepatocellular carcinoma is a highly deadly malignancy, accounting for approximately 800,000 deaths worldwide every year. Mutation of the p53 tumor suppressor gene is a common genetic change in HCC, present in 30% of cases. p53(R175H) (corresponding to p53(R172H) in mice) is a hotspot for mutation t...
Gorde:
| Argitaratua izan da: | PLoS One |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4401698/ https://ncbi.nlm.nih.gov/pubmed/25885474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123816 |
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