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Myc, Aurora Kinase-A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma

Clinical observations, as well as data obtained from the analysis of genetically engineered mouse models, firmly established the gain-of-function (GOF) properties of certain p53 mutations. However, little is known about the underlying mechanisms. We have used two independent microarray platforms to...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Torchia, Enrique C., Caulin, Carlos, Acin, Sergio, Terzian, Tamara, Kubick, Bradley J., Box, Neil F., Roop, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576849/
https://ncbi.nlm.nih.gov/pubmed/21963848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.441
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