Acquisition of relative interstrand crosslinker resistance and PARP inhibitor sensitivity in Fanconi anemia head and neck cancers

PURPOSE: Fanconi anemia (FA) is an inherited disorder associated with a constitutional defect in the FA DNA repair machinery that is essential for resolution of DNA interstrand crosslinks. Individuals with FA are predisposed to formation of head and neck squamous cell carcinomas (HNSCCs) at a young...

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Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Lombardi, Anne J., Hoskins, Elizabeth E., Foglesong, Grant D., Wikenheiser-Brokamp, Kathryn A., Wiesmüller, Lisa, Hanenberg, Helmut, Andreassen, Paul R., Jacobs, Allison J., Olson, Susan B., Keeble, Winifred W., Hays, Laura E., Wells, Susanne I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401632/
https://ncbi.nlm.nih.gov/pubmed/25609062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2616
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