Cargando...

Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Mol Life Sci
Autores principales: Lopez-Martinez, David, Liang, Chih-Chao, Cohn, Martin A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951507/
https://ncbi.nlm.nih.gov/pubmed/27094386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2218-x
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!