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Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

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Bibliografski detalji
Izdano u:Cell Mol Life Sci
Glavni autori: Lopez-Martinez, David, Liang, Chih-Chao, Cohn, Martin A.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951507/
https://ncbi.nlm.nih.gov/pubmed/27094386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2218-x
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