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Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway
Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...
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| Publicado no: | Cell Mol Life Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951507/ https://ncbi.nlm.nih.gov/pubmed/27094386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2218-x |
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