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Processivity of the Kinesin-2 KIF3A Results from Rear Head Gating and Not Front Head Gating

The kinesin-2 family motor KIF3A/B works together with dynein to bidirectionally transport intraflagellar particles, melanosomes, and neuronal vesicles. Compared with kinesin-1, kinesin-2 is less processive, and its processivity is more sensitive to load, suggesting that processivity may be controll...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Chen, Geng-Yuan, Arginteanu, David F. J., Hancock, William O.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400341/
https://ncbi.nlm.nih.gov/pubmed/25657001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628032
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