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Kinesin processivity is gated by phosphate release

Kinesin-1 is a dimeric motor protein, central to intracellular transport, that steps hand-over-hand toward the microtubule (MT) plus-end, hydrolyzing one ATP molecule per step. Its remarkable processivity is critical for ferrying cargo within the cell: over 100 successive steps are taken, on average...

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Bibliografiset tiedot
Päätekijät: Milic, Bojan, Andreasson, Johan O. L., Hancock, William O., Block, Steven M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191751/
https://ncbi.nlm.nih.gov/pubmed/25197045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410943111
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