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Processivity of the Kinesin-2 KIF3A Results from Rear Head Gating and Not Front Head Gating
The kinesin-2 family motor KIF3A/B works together with dynein to bidirectionally transport intraflagellar particles, melanosomes, and neuronal vesicles. Compared with kinesin-1, kinesin-2 is less processive, and its processivity is more sensitive to load, suggesting that processivity may be controll...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400341/ https://ncbi.nlm.nih.gov/pubmed/25657001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628032 |
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